S.H.I.E.L.D. has found a sample of vibranium and have asked Hank Pym to analyze it. But he gets attacked by Klaw and some thugs, who try to steal the vibranium. Although Klaw places the vibranium into a Sonic Disruptor, Ant Man defeats him and his mercenaries. When Wasp arrives to check on Hank, she finds him okay and is asked to make sure the ants don't eat the shrunken mercenaries.
Sometime later, Wasp spots Whirlwind breaking into a college lab and battles him. Ant Man joins later and, while Whirlwind is busy with a swarm of termites, debates with Wasp about whether they should use their powers to help people or leave matters like these to the police. Whirlwind attacks again, Wasp beats him, and she and Ant Man turn Whirlwind over to S.H.I.E.L.D.
Whirlwind is placed in The Big House, a prison Hank Pym designed to rehabilitate people with altered genetics. Nick Fury, who has been trying to get Ant Man to officially join S.H.I.E.L.D., attempts again by offer to make WAsp a S.H.I.E.L.D. agent, which excites her, though she wants Hank on the team as well. Hank refuses again because he's upset that Fury isn't using the Big House for the reasons he desgined it, and he and Wasp leave. Meanwhile, Whirlwind talks to Mad Thinker, who tells him that they don't have to escape because the systems will break down, allowing them to be free again.
Meanwhile, at the African nation of Wakanda, Man-Ape takes the throne after he kills King T'Chaka with help from Klaw. In exchange for his help, Klaw is granted access to the Wakanda's abundant depsoit of vibranium. However, T'Chaka's son, T'Challa, takes up his father's mantle and becomes the new Black Panther.