The Xavier Mansion, also known as the X-Mansion, is the home and headquarters of Charles Xavier aka Professor X and his X-Men. It is also a special school for young and gifted mutants.
Its name was mentioned in an article called "A Secret School For Mutants?" in a newspaper read by a cab driver before his taxi was blown away by The Enchantress posing as Whirlwind just to lure Wasp into a trap in "Masters of Evil".